Cystic Fibrosis Clinical Research

Clinical Research Opportunities:

Unique to the Adult Cystic Fibrosis Clinic at TGH is the opportunity to partcipate in clinical research. Working with pharmaceutical companies, patients of the program have the opportunity to participate in clinical research trials involving new state of the art drugs. Contact our Adult Cystsic Fibrosis coordinator if you are interested in any of the follow studies.

1. Study to Evaluate Lumacaftor and Ivacaftor Combination Therapy in Subjects 12 Years and Older With Advanced Lung Disease

2. A Phase 3 Study to Evaluate the Efficacy and Safety of Ivacaftor and VX-661 in Combination With Ivacaftor in Subjects Aged 12 Years and Older With Cystic Fibrosis, Heterozygous for the F508del-CFTR Mutation

3. A Safety and Efficacy Trial of Inhaled Mannitol in Adult Cystic Fibrosis Subjects 

4. The EPIC Observational Study (EPIC OBS)

5. Prevalence of Antibodies to Selected Porcine Viruses in Patients With Cystic Fibrosis Receiving Porcine-derived Pancreatic Enzyme Replacement Therapy

6. Clearing Lungs With ENAC Inhibition in Cystic Fibrosis

7. Cystic Fibrosis Patient Registry