Lung Allocation Score

The Lung Allocation Score (LAS) is the replacement system for the old accrued time method of lung donor distribution. In this system pre-transplant mortality is weighed with post transplant survival to determine a score that is a surrogate “transplant benefit”. Physiologic parameters such as FVC, O2 requirement, 6 minute walk distance, disease type (COPD vs. CF vs. IPF) and PCO2 are used in the calculation of pre-transplant mortality.

Statistically patients with IPF and CF are less likely to survive to transplant then a patient with COPD and the same physiologic parameters. The patient with CF and UIP will then receive a higher LAS then the patient with COPD and hence are more likely to receive a transplant then the patient with COPD. Intuitively this will shift the demographics of transplant recipients in this country from one with a predominance of patients with COPD being transplanted, to one in which a larger percentage patients with UIP and CF will be transplanted.

A pamphlet about the Lung Allocation Score from the United Network for Organ Sharing may be downloaded from here.

More information: TGH Lung Transplant Referral Guide