Physician Publications

Mark Rolfe, MD, FCCP

Publications
Rolfe, MW., Kunkel, SL., Standiford, TJ., Chensue, SW., Allen, RM., Evanoff,H., Phan, S., Strieter, RM. Pulmonary Fibroblast Expression of Interleukin-8: A Model for Alveolar Macrophage-Derived Cytokine Networking. Am J Respir Cell Molec Biol. 5: 493-501, 1991.

Standiford, TJ., Kunkel, SL., Kasahara, K., Milia, M., Rolfe, MW., Strieter, RM. IL-8 Gene Expression from Human Alveolar Macrophages: The Role of Adherence. Am J Respir Cell Molec Biol. 5: 579-585, 1991.

Ham, JM., Kunkel, SL., Dibb, CR., Standiford, TJ., Rolfe, MW., Strieter, RM. Chemotactic Cytokines (IL-1 and MCP-1) Gene Expression by Human Whole Blood. Invest Immunol. 20: 387-394, 1991.

Rolfe, MW., Strieter,RM., and Lynch,JP. Chronic Pulmonary Infections: Nocardiosis. Semin Respir. Med. 13; 216-233, 1992.

Rolfe, MW., Kunkel, SL., Rowens, B., Standiford, TJ., Strieter, RM. Amiloride Suppression of Human Alveolar Macrophage-Derived Cytokines. Am J Respir Cell Molec Biol. 6; 576-582, 1992.

Lynch, J.P., Rolfe, M.D. When- and How- to be Alert for Nocardiosis. The Journal of Respiratory Diseases 13: 12: 1695-1714.1992.

Strieter, RM., Chensue SW., Standiford TJ., Lynch JP., Rolfe MW.Kunkel SL. Chronic Pulmonary Infections: Host Response in Granulomatous Inflammation of the Lung. Semin Resp Med. 13; 149-157, 1992.

Standiford, TJ., Kunkel, SL., Rolfe, MW., Evanoff, HL., Allen, RM., Strieter, RM. Regulation of Human Alveolar Macrophage- and Blood Monocyte-derived Interleukin-8 by Prostaglandin E2 and Dexamethasone. AmJ Respir Cell Molec Biol. 6: 1, 75-81, 1992.

Lynch, JP. lll, Standiford, TJ., Rolfe, MW., Kunkel, SL., Strieter RM. Neutrophilic Alveolitis in Idiopathic Pulmonary Fibrosis: The Role of Interleukin-8. Am. Rev. Resp. Dis. 145: 6, 1433-1439, 1992.

Moore, SA., Strieter, RM., Rolfe, MW., Standiford, TJ., Burdick, MD., Kunkel,SL. The Expression and Regulation of Human Alveolar Macrophage-Derived Interleukin-1 Receptor Antagonist. Am J Respir Cell Molec Biol. 6: 6, 569-582, 1992.

Rolfe, MW., Paine, R., Davenport, RD., Strieter, RM. Hard Metal Pneumoconiosis and the Association of Tumor Necrosis Factor. Am. Rev. Resp. Dis. 146; 1600-1602, 1992.

Rolfe, MW., Kunkel, SL., Standiford, TJ., Phan, S.,Burdick, MD., Evanoff, HL., Strieter, RM. Expression and Regulation of Human Pulmonary Fibroblast-Derived Monocyte Chemotactic Protein-1 (MCP-1). Am J Phys: Lung Cellular and Molecular Physiology , L536-545, 1992.

Strieter, RM., Kasahara, K., Allen, RM., Standiford, TJ., Rolfe, MW., Becker, FS., Chensue, SW., Kunkel, SL. Cytokine-induced Neutrophil-derived Interleukin-8. Am. J. Pathol 141: 397-407, 1992.

Strieter, RM., Standiford, TJ., Rolfe, MW., Kasahara, K., and Kunkel, SL. Regulation of Human Alveolar Macrophage and Blood Monocyte-Derived TNF and IL-8: The Role of PGE2, Dexamethasone, Amiloride, and IL-4. Sarcoidosis, Suppl. 1, 9; 195-198, 1992.

Strieter, RM., Kasahara, K., Allen, RM., Standiford, TJ., Rolfe, MW., Becker, FS., Chensue, SW., Kunkel, SL. Cytokine-Induced Neutrophil derived Interleukin-8. Am. J. Path. 141, 2; 357-407, 1992.

DeMeester, SR., Rolfe, MW., Kunkel, SL., Swiderski, DL., Lincoln, PM., Deeb, GM, Strieter, RM. The Bimodal Expression of Tumor Necrosis Factor- Alpha in Association with Rat Lung Allograft Reimplanatation and Allograft Rejection. J. Immunol. 150, 6; 2494-2450, 1993.

Rolfe, MW., Standiford, TJ., Kunkel, SL., Burdick, MD., Gilbert, AR., Lynch, JP. III, Strieter, RM. Interkeukin-1 Receptor Antagonist Expression in Sarcoidosis. Am. Rev. Resp. Dis. 148, 5; 1378-1384, 1993.

Smith, DR., Kunkel, SL., Standiford, TJ., Chensue, SW., Rolfe, MW., Orringer, MB., Whyte, RI., Burdick, MD., Danforth, JM., Gilbert, AR., and Strieter, RM. The Production of Interleukin-1 Receptor Antagonost by Human Bronchogenic Carcinoma. Am. J. Path. 143 (3) 794-803, 1993.

Wakefield, TW., Greenfield, LJ., Rolfe, MW., DeLucia, A., Strieter, RM., Abrahms, GD., Kunkel, SL., Esmon CT., Wrobleski, SK., Kadell, AM., Burdick, MD., Taylor FB. Inflammatory and Procoagulant Mediator Interactions in an Experimental Baboon Model of Venous Thrombosis. Thrombosis and Hemostasis, 69, 2; 164-172, 1993.

Paine, RP., Rolfe, MW., Standiford, TJ., Burdick, MD., Rollins, BJ., Strieter, RM. MCP-1 Expression by Rat Type II Alveolar Epithelial Cells in Primary Culture. J. Immun. ,150, 10; 4561-4570, 1993.

Rolfe, MW., Standiford, TJ., Kunkel, SL., Burdick, MD., Lynch, JP. III, and Strieter, RM. Interleukin-1 Receptor Antagonist Expression in Sarcoidosis. Am. Rev. Resp. Dis. 148, 5; 1378-1384, 1993.

Rolfe, MW., Kunkel, SL., DeMeester, SR., Swiderski, DL., Lincoln, PM., Deeb, GM., and, Strieter, RM. Expression of Interleukin-6 in Association with Rat Lung Reimplantation and Allograft Rejection. Am. Rev. Resp Dis. 147, 4; 1010-1016, 1993.

Cornblath, WT., Elner V, Rolfe, MW. Extraocular Muscle Involvement in Sarcoidosis. Opthalmology 100, 4; 501-505, 1993.

Standiford, TJ., Rolfe, MW., Kunkel, SL., Becker, F., Lynch, III, JP., Orringer, M., Phan, S., Strieter, RM. Altered Production and Regulation of Monocyte Chemoattractant Protein-1 from Pulmonary Fibroblasts Isolated From Patients with Idiopathic Pulmonary Fibrosis. Chest 103: 2; 121S, 1993.

Rolfe, MW., DeMeester, S., Kunkel, SL., Lincoln, P., Deeb, M., Lupinetti, F., Strieter, RM. Lung Allograft Rejection: The Role of IL-6 and TNF. Chest 103: 2; 133S, 1993.

Christensen, P.J., Rolfe, M.W., Standiford, T.J., Burdick, M.D., Toews, G.B., Strieter, R.M. Characterization of the Production of Monocyte Chemoattractant Protein-1 (MCP-1) and Interleukin-8 (IL-8) in an Allogeneic Immune Response. J. Immunol. 151 (3) 1205-1213,1993.

Standiford, TJ., Rolfe, MW., Kunkel, SL., Lynch,III, JP., Burdick, MD., Gilbert,AR., Orringer, MB., Strieter, RM. Macrophage Inflammmatory Peptide-1 Expression in Interstitial Lung Disease. J. Immunol. 151 (5); 2852-2863, 1993.

Liebler, J.M., Kunkel, S.L., Burdick, M.D., Standiford, T.J., Rolfe, M.W., Strieter, R.M. The Production of IL-8 and MCP-1 by Peripheral Blood Monocytes: Disparate Responses to PHA and LPS. J. Immunl. 152, 1; 241-149, 1994.

Alberts, WM., Rolfe, MW. A Step Care Approach to Managing COPD. Hospital Formulary 29 (11) 756-766, 1994. Rolfe, MW., Schnapf, B. Management of the Adult Patient with Cystic Fibrosis . Clin Pulm Med. 2(2): 75-87, 1995.

Smith, DR., Kunkel SL., Standiford, TJ., Rolfe MW., Lynch, JP., Arenberg,DA., Wilke, CA, Burdick, MD, Martinez, FJ., Hampton,JN., Whyte RI., Orringer, MB., and Strieter, RM. Increased Interleukin-1 Receptor Antagonist in Idiopathic Pulmonary Fibrosis; A Compartmental Analysis. Am. J. Respir .Crit. Care Med. 151: 1965-1973, 1995.

Rolfe, MW, Alberts WM. The Chronic Persistent Cough. Comprehensive Therapy. 10 : 615-21, 1996.

Robinson LA, Rolfe MW. “Keeling Syndrome” – A Late Complication of Pneumonectomy. N Engl J Med. 3; 335 (14): 1074. 1996

Rumbak MJ, Walsh FW, Anderson WM, Rolfe MW, Solomon D. Significant Tracheal Obstruction Causing Failure to Wean in Patients Requiring Prolonged Mechanical Ventilation. Chest 1999 (In Press)

Book Chapters

Strieter, RM., Standiford, TJ., Rolfe, MW., Lynch, JP lll., Metinko, A., Kunkel,S., Cytokines in Pulmonary Injury. In: Cytokines in Health and Disease: Physiology and Pathophysiology, Marcel Dekker, Inc., New York, 1991.

Kunkel, SL, Standiford, TJ, Rolfe, MW., Strieter, RM. The Role of Chemotactic Cytokines in Diverse Pathophysiological Diseases. In: Mantovani A, Ghezzi P (eds). Pathophysiology and Pharmacology of Cytokines, Biomedical Press, New York, 1992.

Kunkel, SL., Rolfe, MW., Strieter, RM. Expression of Tumor Necrosis Factor during Lung Allograft Revascularization and Rejection. In: Fers and Burman V. (eds). Proceedings of the Fourth International TNF Congress. Springer-Verlag, Heidelberg, Germany, 1992.

Strieter, RM., Colletti, LM., Metinko, AP., Rolfe, MW., DeMeester, SR., Standiford, TJ., Kunkel, SL. The Role of Cytokine Networks Mediating Inflammation and Ischemia-Reperfusion Injury. In; Schlag G., Redl, H. (ed). Third Wiggers Bernard Conference on Shock, Sepsis, and Organ Failure. 1992.

Strieter, RM., Standiford, TJ., Rolfe, MW., Kunkel, SL. Interleukin-8. In: Kelley J (ed). Cytokines of the Lung: Lung Biology in Health and Disease, Marcel Dekker, Inc., New York, 281-305, 1993.

Walsh FW, Rolfe MW, Rumbak MJ. The Initial Pulmonary Evaluation of the Immunocompromised Patient. In: Chest Surgery Clinics of North America: Thoracic Disorders in the Immunocompromised Patient. 9: 1; 19-39, 1999.

Rolfe MW, Tockman M, Lung Cancer in the Geriatric Patient. Merck Manual of Geriatric Medicine 1999.

Clark R, Hazelton T, Coppage L, Chirikos T, Walsh F, Rolfe MW, Robinson LA, Sommers E, Berman G, Eikman E, Wadhwa N, Bepler G, Krischer J, Tockman MS. Lung Cancer Screening with Computed Tomography: Interim Results of a Cohort Screening Trial. Radiology 2004 (in press)

Abstracts

Rolfe, MW., Kunkel, SL., Standiford, TJ., Chensue, SW., Allen, RM., Evanoff, HL., Phan, S., and Strieter, RM. Interleukin-8 Expression by Pulmonary Fibroblasts: A Model of Cellular Communication. Clin Res 39: 14A, 1991.

Rolfe, MW., Kunkel, SL., Standiford, TJ., Allen, RM., Chensue, SW., Evanoff, HL., and Strieter, RM. Human Pulmonary Fibroblasts Express of Interleukin-8: A Model of Cellular Communication. Clin. Res. 5: 6, A6205 , 1991.

Rolfe, MW., Kunkel, SL., Standiford, TJ., Allen, RM., Evanoff, HL., and Strieter, RM. Interleukin-8 Expression by Human Hulmonary Fibroblasts: A Model of Cellular Communication. Am. Rev. Resp. Dis. 143 : A525, 1991.

Rolfe, MW., DeMeester, SR., Kunkel, SL., Deeb, MG., Lupinetti, FM., Strieter, RM. Compartmentalized Expression of Tumor Necrosis Factor During Rat Lung Allograft Rejection. Clin Res 39: 3728A, 1991. Allen, RM., Kunkel, SL., Rollins, B., Standiford, TJ., Rolfe, MW., and Strieter,RM. 1991.

Stimulation of Human Mononuclear Phagocytes by Monocyte Chemotactic Peptide (MCP-1). FASEB J 5: A975, 1991. Allen, RM., Kunkel, SL., Rollins, B., Standiford, TJ., Rolfe, MW., and Strieter, RM. Stimulation of Human Mononuclear Phagocytes by Monocyte Chemotactic Peptide (MCP-1). Am. Rev. Resp. Dis. 143: 4, A232, 1991.

Lynch, JP., Standiford TJ., Kunkel SL., Rolfe, MW., and Strieter, RM. Interleukin-8 Gene Expression is Augmented in Idiopathic Pulmonary Fibrosis and Correlates with Neutrophil Alveolitis. Am. Rev. Resp. Dis. 143:A396, 1991.

Standiford, TJ., Kunkel, SL., Rolfe, MW., Kasahara, K., and Strieter, RM. IL-4 Differentially Regulates the Expression of TNF, IL-1b, and IL-8 from Human Peripheral Blood Monocytes and Alveolar Macrophages. Am. Rev. Resp. Dis. 143: A232, 1991.

Rolfe, MW., Kunkel, SL., Standiford, TJ., Becker, FS, Gilbert, AR., Evanoff, HL., Burdick, MD., and Strieter, RM. Human Pulmonary Fibroblasts Express Monocyte Chemoattractant Peptide-I (MCP): A Model of Cellular Communication. Clin. Res. 4: A941, 1992.

Moore, SA., Strieter, RM., Rolfe, MW., Burdick, MD., and Kunkel, SL. Disparate Expression of IRAP in Sarcoid Alveolar Macrophages. Clin. Res. 4: A1205 1992.

Becker, FS., Standiford, TJ., Rolfe, MW., Gilbert, AR., and Strieter, RM. Interleukin-4 Regulates the Production of Interleukin-8 from Neutrophils. Clin. Res. 5: A1895, 1992.

Rolfe, MW., Kunkel, SL., Standiford, TJ., Becker, FS, Evanoff, HL.,Burdick, MD., and Strieter, RM. Expression and Regulation of Human Pulmonary Fibroblast-Derived Monocyte Chemotactic Peptide-1. Am. Rev. Resp. Dis. 145: 4 : A235 , 1992.

Rolfe, MW., DeMeester, SR., Kunkel, SL., Swiderski, DL., Lincoln, PM., Deeb, GM., and Strieter, RM. Interleukin-6 and Tumor Necrosis Factor-Alpha Expression During Rat Lung Allograft Rejection. Am. Rev. Resp. Dis. 145: 4 : A308, 1992.

Rolfe, MW., Kunkel, SL., Rowens, B., Standiford, TJ., Strieter, RM. Suppression of Human Alveolar Macrophage-Derived Cytokines by Amiloride. Am. Rev. Resp. Dis. 145: 4: A181 1992.

Paine, R., Rolfe, M., Rollins, B., Strieter, R. Expression of Monocyte Chemotactic Peptide-1 (MCP-1) by Rat Type II Epithelial Cells In Vitro. Am. Rev. Resp. Dis. 145: 4 A133, 1992.

Neagos, GR., Rolfe, MW., Lynch, JP. Thoracic Actinomycosis Caused by A. Odontolyticus: A Report of Four Cases and A Review of the Literature. Am. Rev. Resp. Dis. 145: 4 A547, 1992.

Moore, SA., Strieter, RM., Rolfe, MW., Becker, FS., Kunkel, SL. Disparate Expression of IRAP in Sarcoid Alveolar Macrophages. Clin. Res. 6:A1205, 1992.

Wertheim, WA., Becker, FS., Gilbert, AR., Standiford, TJ, Rolfe, MW., Strieter, RM. Regulation of Neutrophil-Derived Interleukin-8 by Dexamethasone and Prostaglandin E2. Clin Res 40: 306A, 1992.

Smith, DR., Kunkel, SL., Rolfe, MW., Standiford, TJ., Orringer, MB., Whyte, RI., Burdick, MD., Gilbert, AR., Walz, A., Strieter, RM. Chemotactic Cytokines Associated with Human Bronchogenic Carcinoma. Am. Rev. Resp. Dis. 147, 4; A331, 1993.

Standiford, TJ., Rolfe, MW., Kunkel, SL., Lynch, JP., Burdick, MD., Gilbert, AR., Orringer, MB., Strieter, RM. Macrophage Inflammatory Protein 1 Expression in Interstitial Lung Disease. Am. Rev. Resp. Dis. 147, 4; A479, 1993.

Strieter, RM., Swiderski, DL., Rolfe, MW., DeMeester, SR., Burdick, MD., Deeb, GM., Kunkel, SL. Cytokines in Lung Transplantation; The Role of TNF and IL-6. British Association for Lung Research; Cytokines and the Lung. Respiratory Medicine 1993.

Berger M., Nadel J., Gadek J., Eisenberg J, Rolfe M, Rousell R, Pennington J. Aerosolized Prolastin (Alpha1-Protease Inhibitor) in Cystic Fibrosis. Pediatric Pulmonary 12: 26, 1995.

Calderon E, Naderson WM, Rolfe MW, Rumbak MJ, Overton RM, Z Liu, Vesely DL. Dexamaethasone Increases the Production of Vessel Dilator in Pulmonary Epithelial Cells. Am J Resp Crit Care Med. 157: A 195, 1998.

Calderone E, Anderson Wm. Rolfe MW, Rumbak M, Overton RM, Liu Z, Vesely DL. Dexamethasone Increases the Production of Vessel Dilator in Pulmonary Epithelial Cells. Am J Pulm Crit Care 1998 (supplement)

Zhi Liu, Calderone E, Rolfe MW, Rumbak M, Anderson Wm. Platelet- activating Factor Induces Protein Kinase C Activation in CALU-1 Cells. Am J Clin Pathol 1999 (supplement)

Orlando DA, Hoffberger D, Walsh F, Rolfe MW, Bomba JJ, Tockman MS. Quantification of Autofluoresence Bronchoscopy Supplements the Interpretation of Precancerous Lesions. Chest 03-663 2003.

Clum SR, Rolfe MW, Solomon D. Idiopathic Pleuroparenchymal Fibroelastosis: Trials and Tribulations Following Single Lung Transplantation. Chest 4:132 2007
Tarik Haddad , MD, FCCP

Publications

9/08
Ferguson R, Phelan T, Haddad T, Hinduja A, Dubin A. Survival After In-Hospital Cardiopulmonary Resuscitation. Southern Medical Journal. 2008 Sept [Epub ahead of print].

3/07
Mankidy B, Kesavan RB, Silay YS, Haddad TJ, Seethamraju H. Emerging Drugs in Lung transplantation. Expert Opin Emerg Drugs. 2007 Mar;12(1):61-73.

Abstracts/Presentations:

10/07
American College of Chest Physicians CHEST Meeting 2007 – Chicago, Illinois Oral Organ Transplant Case Presentation: “A Rare Cause of Acute Cor Pulmonale in Lung Transplantation”
– Oral Lung Transplantation Presentation: “A Novel Clinical Presentation of Bronchiolitis Obliterans”
– Oral Lung Transplantation Innovations Presentation: “Vanishing Bronchus Syndrome”
– Oral Lung Transplantation Innovations Presentation: “Impact of Airway Complication on Lung Function in Post Lung Transplant Patients”

4/07
American Transplant Congress for Poster Presentation 2007 San Francisco, California; “The Incidence, Impact, and Treatment of Humoral Rejection in Lung Transplant”

10/06
American College of Chest Physicians CHEST Meeting 2006 Salt Lake City, Utah
– Oral Cancer Case Presentation: “Thymic Carcinoid Presenting as a Posterior Mediastinal Mass”

11/05
Southern Medical Association San Antonio, Texas 2005 Meeting
– Oral Research Presentation: “Clinical and Epidemiological Profiles of Bacterial and Fungal Meningitis in Two Baltimore Hospitals”

5/04
American College of Physicians – Maryland Chapter Meeting, Baltimore, MD
– Research Poster Presentation: “Clinical and Epidemiological Profiles of Bacterial and Fungal Meningitis in 2 Baltimore Hospitals”
– Case Report Poster Presentation: “Fatal Hemorrhage From a Rare Etiology”
– Research Poster Presentation: “CPR Outcomes: When should resuscitation be stopped?”

11/02
Southern Medical Association, Washington, DC 2002 Meeting
– Oral Case Presentation: “An Unusual Case of Vertebral Artery Dissection”

5/02
American College of Physicians – Maryland Chapter Meeting, Baltimore, MD
– Poster Presentation: “An Unusual Case of Vertebral Artery Dissection”
– Poster presentation: “Energy Boosters: The Disheartening Truth”

Timothy Floreth, MD

Publications:

Floreth, T and Bhorade SM. “Special Considerations in Lung Transplantation in Older Patients.” Aging and Lung Disease. Ed. M Pisani.

Floreth, T, Ahya V, and Bhorade SM. “Conventional and Novel Approaches to Immunosuppression.” Clinics in Chest Medicine, 2011.

Stern E, Floreth T, Yingli T, Stern R, Garrity ER, Bhorade SM, and White SR. “Differentiated Transplant Derived Airway Epithelial Cell Cytokine Secretion Is Not Regulated By Cyclosporine” Respiratory Research. 2011

Floreth, T. and Bhorade, S. “Current Trends in Immunosuppression in Lung Transplantation.” Seminars in Respiratory and Critical Care Medicine 31 (2010): 172-178

Abstracts/Presentations:

Floreth, T, Stern R, Laxman B, and White SR. “Interleukin-10 Inhibits HLA-G Expression in Differentiated Human Airway Epithelium Cells.” ATS 2011. Poster Presentation.

Floreth, T, Stern R, Laxman B, Garrity ER, Bhorade SM, and White SR. “Human Leukocyte Antigen-G Concentrations in Plasma and BALF Are Inversely Correlated to High Grade Rejection in Lung Transplant” ISHLT 2011. Oral Presentation.

Floreth, T. “HLA-G in Lung Epithelium and Its Potential Role in Promoting Allograft Survival” University of Chicago, 2010. Lecture

Floreth, T. “The Guys from Guys.” History of Medicine Lecture Series. Pritzker School of Medicine, University of Chicago. 2006. Lecture.

Floreth, T. “The Effect of Phytochemicals on Natural Killer Cells.” Research Day. University of Illinois at Chicago College of Medicine. 2003. Poster.

Floreth, T. “The Effect of CD4 on Determining TH1 versus TH2 Fate.” Honors Thesis and Graduation with Distinction Poster Presentation. Duke University. 1999. Poster.

Book Chapters:

Floreth, T. “Ch 17: Interpretation of Hemodynamic Waveforms.” Just the Facts in Critical Care. Eds. GA Schmidt and JB Hall. McGraw-Hill, 2007. Print.